01 — Cosmetics

Zeyton cosmetics - Skin Care

Zeyton's hydroxytyrosol-rich olive extracts are ideal cosmetic formulations, providing formulation stability, consistent performance, and experimentally supported cosmetic positioning.

In-Vivo Skin Lightening trial

Volunteers10 volunteers
PopulationM/F 23-45, free of skin pathologies
Duration28 days
Application2 mg to forearm, twice daily
Timepoints0, 3, 8, 14, 28 days
VehiclesBase Cream/Serum control; +3.5% Zeyton 5; +3.5% Zeyton 6

Key outcome

15%

reduction in melanin index at 28 days vs untreated skin with 3.5% Zeyton 5 (liquid) or Zeyton 6 (powder). Non-invasive, safe, well-tolerated.

Relevant for claims: “helps reduce appearance of hyperpigmentation” / “contributes to brighter skin tone”
ROS

30–50% inhibition

of reactive oxygen species (ROS) in standardized in-vitro assays

TYR

Up to 96% tyrosinase inhibition

mechanistic basis for oxidative stress defense and tone-evenness

02 — Hydroxytyrosol

Heart Care Supplement- Cholesterol Protection

Cholesterol is an essential fat for the good functioning of the body. In addition to being produced by the body, cholesterol is obtained from food.

Cholesterol is carried in the bloodstream by lipoproteins. Low-density lipoproteins (LDL) carry cholesterol from the liver and intestine to muscle and organ tissues. It is the process of LDL oxidation that generates deposition of fat in arteries – atherosclerosis – and its consequences: hypertension, heart failure, angina pectoris, acute myocardial infarction, cerebral-vascular accident.

“It has been proved that olive polyphenols protect LDL from oxidation”

Hence, while traditional “cholesterol” treatments wage on lowering LDL levels, reducing effect of fat deposition, the effect of olive polyphenols (HT) is to prevent that deposition.

Mechanism

LDL→Oxidation→Arterial Deposition
LDL+HT→Protected

EFSA Verified Claim — 2011

“Consumption of olive oil polyphenols contributes to the protection of blood lipids from oxidative damage”

EFSA Journal 2011; 9(4):2033. Authorised when product contains at least 5 mg hydroxytyrosol and derivatives (oleuropein complex, tyrosol) per 20 g olive oil. Beneficial effect with daily intake of 20 g olive oil.

Zeyton 5: ≥5% HT+tyrosol (≥4% HT) — liquidZeyton 6: ≥6% HT+tyrosol (≥5% HT) — powder, maltodextrin excipient